Sialic Acid Binding Ig Like Lectin 1 (SIGLEC1) Antibody (APC)
429€ (100 tests)
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Name
Sialic Acid Binding Ig Like Lectin 1 (SIGLEC1) Antibody (APC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx140471
Tested Applications
FCM
Description
SIGLEC1 Antibody is a Mouse Monoclonal against SIGLEC1.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Sialic Acid Binding Ig Like Lectin 1 (SIGLEC1) Immunogen: Human rhinovirus 14-infected monocyte-derived dendritic cells. |
| Host | Mouse |
| Reactivity | Human |
| Detection Method | Laser Line: 647 Excitation/Emission: 651/660 |
| Recommended Dilution | FCM: 10 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | APC |
| Isotype | IgG1 |
| Clone ID | M408 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q9BZZ2 |
| Gene ID | 6614 |
| Alias | SN,CD169,SIGLEC-1,Sialoadhesin |
| Background | Antibody anti-SIGLEC1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
SIGLEC1, also known as sialoadhesin, is a member of the Siglec family of sialic acid-binding immunoglobulin-like lectins. It is primarily expressed on macrophages and functions in cell-cell interactions, particularly in the immune system. SIGLEC1 recognizes sialylated glycoconjugates on the surface of other cells, facilitating phagocytosis and immune surveillance. It is highly expressed in inflammatory and infectious conditions, playing a role in pathogen recognition.
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