SHARPIN (SHARPIN) Antibody (HRP)

Product Graph
169€ (20 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
SHARPIN (SHARPIN) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx337670
tested applications
ELISA

Description

SHARPIN Antibody (HRP) is a Rabbit Polyclonal against SHARPIN.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

CategoryPrimary Antibodies
Immunogen TargetSHARPIN (SHARPIN)
HostRabbit
ReactivityHuman
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationHRP
IsotypeIgG
Purity> 95%
PurificationPurified by Protein G.
Size 120 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 51 mg
FormLiquid
Tested ApplicationsELISA
Buffer0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ9H0F6
Gene ID81858
BackgroundAntibody anti-SHARPIN
StatusRUO

Descripción

Related Products

EH12274

Human SHARPIN(Sharpin) ELISA Kit

Ver Producto
FNab07838

anti- SHARPIN antibody

Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex(TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.

Ver Producto
FNab10251

anti- SHARPIN antibody

Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex(TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.

Ver Producto