Sh3-Domain Binding Protein 4 (SH3BP4) Antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Sh3-Domain Binding Protein 4 Antibody is a Rabbit Polyclonal antibody against Sh3-Domain Binding Protein 4.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Sh3-Domain Binding Protein 4 (SH3BP4) Immunogen: Human SH3BP4. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P0V3 |
| Gene ID | 23677 |
| NCBI Accession | NP_055336.1, NM_014521.2 |
| OMIM | 605611 |
| Background | Antibody anti-SH3BP4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Related Products

SH3BP4 antibody
May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.
Ver Producto
Recombinant Human SH3BP4
Ver Producto
SH3 Domain Binding Protein 4 (SH3BP4) Antibody
This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor.
Ver Producto