SET And MYND Domain-Containing Protein 3 (SMYD3) Antibody
312€ (60 µl)
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935106861
info@markelab.com
name
SET And MYND Domain-Containing Protein 3 (SMYD3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx005516
tested applications
IF/ICC
Description
SMYD3 Antibody is a Rabbit Polyclonal antibody against SMYD3. This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | SET And MYND Domain-Containing Protein 3 (SMYD3) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H7B4 |
| Gene ID | 64754 |
| NCBI Accession | NP_073580.1 |
| OMIM | 608783 |
| Background | Antibody anti-SMYD3 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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SMYD3 antibody
Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di-and tri-methylation, but not monomethylation(PubMed:15235609, PubMed:22419068). Also methylates 'Lys-5' of histone H4(PubMed:22419068). Plays an important role in transcriptional activation as a member of an RNA polymerase complex(PubMed:15235609). Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences(PubMed:15235609).
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