Serum Paraoxonase/arylesterase 2 (PON2) Peptide

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Description
Serum Paraoxonase/arylesterase 2 (PON2) Peptide is a synthetic peptide.
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Product specifications
Category | Proteins and Peptides |
Immunogen Target | Serum Paraoxonase/arylesterase 2 (PON2) |
Host | Synthetic |
Recommended Dilution | BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Observed MW | Sequence Fragment: Internal region: C-ERLLALRNRLKAS |
Size 1 | 100 µg |
Form | Lyophilized Reconstitute in deionized water. |
Tested Applications | P-ELISA |
Buffer | Prior to lyophilization: Deionized water. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Gene ID | 5445, 330260, 296851 |
NCBI Accession | NP_000296.2, NP_001018171.1 |
Background | Protein PON2 |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
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