Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Antibody (FITC)

Este producto es parte de SERPINF1 - serpin family F member 1
Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Antibody (FITC)

Pida mas información

935106861

info@markelab.com

Precio

162.5€ (20 µg)

proveedor

Abbexa

reference

abx319705

Tested Applications

reactivity

Rat

status

RUO

clonality

Polyclonal

Descripción

Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Antibody (FITC) is a Rabbit Polyclonal against Pigment Epithelium-Derived Factor / PEDF (SERPINF1) conjugated to FITC.

Background

Inhibitory serpins have been shown to function in processes as diverse as DNA binding, chromatin condensation, immunoregulation ,apoptosis and haemostasis. Serpins are a broadly distributed protease inhibitors that use the conformational change as a mechanism of action. They are central in controlling many important proteolytic cascades. Phylogenetically Serpins superfamily organized in "Clades", named by letters. The following numbers shows the position in the glade. Serpin named as a SERPINXy, (where X is the clade and y is the number within that clade) many serpins also have alternative names from before this classification was proposed. Structuraly Serpinsare three β-sheets (A, B and C), 8-9 α-helices (termed hA-hI) and the reactive center known as reactive center loop (RCL). Pigment epithelium-derived factor (PEDF) also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functions

Background

Se ha demostrado que las serpinas inhibidoras funcionan en procesos tan diversos como la unión al ADN, la condensación de cromatina, la inmunorregulación, la apoptosis y la hemostasia. Las serpinas son inhibidores de proteasas ampliamente distribuidos que utilizan el cambio conformacional como mecanismo de acción. Son fundamentales para controlar muchas cascadas proteolíticas importantes. Filogenéticamente superfamilia de Serpinas organizada en "Clados", nombradas por letras. Los siguientes números muestran la posición en el claro. Serpin nombrada como SERPINXy (donde X es el clado e y es el número dentro de ese clado). Muchas serpinas también tienen nombres alternativos antes de que se propusiera esta clasificación. Estructuralmente, las Serpins son tres láminas β (A, B y C), 8-9 hélices α (denominadas hA-hI) y el centro reactivo conocido como bucle del centro reactivo (RCL). El factor derivado del epitelio pigmentario (PEDF), también conocido como serpina F1 (SERPINF1), es una proteína secretada multifuncional que tiene funciones antiangiogénicas, antitumorales y neurotróficas.

Características del producto

category

Primary Antibodies

clonality

Polyclonal

reactivity

Rat

immunogen target

Pigment Epithelium-Derived Factor / PEDF (SERPINF1)

host

Rabbit

conjugation

FITC

form

Liquid

purity

> 95%

purification

Purified by Protein G.

buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.

size 1

20 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

1 mg

storage

Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.

or code

SERPINF1

dry ice

No

availability

Shipped within 5-10 working days.

alias

OI6,OI12,PEDF,EPC-1,PIG35,Pigment epithelium-derived factor,Cell proliferation-inducing gene 35 protein,Serpin F1

uniprot id

https://www.uniprot.org/uniprotkb/Q80ZA3

gene id

https://www.ncbi.nlm.nih.gov/gene/287526

note

This product is for research use only.

Quizá le pueda interesar

Human Pigment Epithelium-Derived Factor / PEDF (SERPINF1) ELISA Kit

Human Pigment Epithelium-Derived Factor / PEDF (SERPINF1) ELISA Kit

proveedor

Abbexa

reference

abx152695

Tested Applications

ELISA

reactivity

Human

status

RUO

Human Pigment Epithelium Derived Factor / PEDF (SERPINF1) ELISA Kit is an ELISA Kit for the in vitro quantitative measur...

662.5€ (96 tests)

Ver más

Mouse Pigment Epithelium-Derived Factor / PEDF (SERPINF1) ELISA Kit

Mouse Pigment Epithelium-Derived Factor / PEDF (SERPINF1) ELISA Kit

proveedor

Abbexa

reference

abx154524

Tested Applications

ELISA

reactivity

Mouse

status

RUO

Mouse Pigment Epithelium Derived Factor / PEDF (SERPINF1) ELISA Kit is an ELISA Kit for the in vitro quantitative measur...

675€ (96 tests)

Ver más

Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Antibody (HRP)

Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Antibody (HRP)

proveedor

Abbexa

reference

abx319704

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Polyclonal

Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Antibody (HRP) is a Rabbit Polyclonal against Pigment Epithelium-Der...

162.5€ (20 µg)

Ver más