Serpin Peptidase Inhibitor, Clade A Member 8 Protein
234€ (2 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Serpin Peptidase Inhibitor, Clade A Member 8 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262647
tested applications
SDS-PAGE
Description
SERPINA8 is a recombinant protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | SERPINA8 |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P01019 |
| Alias | ANHU,SERPINA8,hFLT1 |
| Background | Protein AGT |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Angiotensinogen (AGT) is a protein primarily produced and secreted by the liver, although it is also synthesized by other tissues, including the kidney and adipose tissue. It serves as the precursor molecule for the renin-angiotensin system (RAS), a key regulatory pathway involved in blood pressure regulation, fluid balance, and electrolyte homeostasis. AGT is converted into angiotensin I by the enzyme renin, which is released by the kidneys in response to various stimuli, such as decreased blood pressure or sodium levels. Angiotensin I is further converted into angiotensin II by angiotensin-converting enzyme (ACE), leading to vasoconstriction, aldosterone release, and sodium reabsorption, ultimately raising blood pressure. Dysregulation of the RAS, including alterations in AGT levels, has been implicated in hypertension, cardiovascular disease, and kidney disorders. Therapeutic interventions targeting the RAS, such as ACE inhibitors and angiotensin receptor blockers, are commonly used to manage hypertension and related conditions. Understanding the role of AGT in the RAS provides insights into cardiovascular health and potential avenues for therapeutic intervention. Ongoing research continues to elucidate the intricate mechanisms underlying AGT regulation and its implications for human health and disease
Related Products
Thyroxine Binding Globulin / TBG (SERPINA7) Antibody
SERPINA7 is a major thyroid hormone transport protein in serum.
Ver Producto
Rat Thyroxine Binding Globulin / TBG (SERPINA7) ELISA Kit
Rat Thyroxine Binding Globulin / TBG (SERPINA7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Thyroxine Binding Globulin / TBG (SERPINA7) concentrations in Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Ver Producto