Serpin I2 (SERPINI2) Antibody
637€ (100 µl)
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935106861
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name
Serpin I2 (SERPINI2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx115479
tested applications
ELISA, WB
Description
Serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2 Antibody is a Rabbit Polyclonal antibody against Serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Serpin I2 (SERPINI2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75830 |
| Gene ID | 5276 |
| OMIM | 605587 |
| Alias | MEPI,PI14,PANCPIN,TSA2004,Serpin I2,Myoepithelium-derived serine protease inhibitor,Pancpin,Peptidase inhibitor 14 |
| Background | Antibody anti-SERPINI2 |
| Status | RUO |
Descripción
SERPINI2 is a member of the serine protease inhibitor (serpin) family and is encoded by the SERPINI2 gene located on chromosome 3. The serpin superfamily comprises a large group of proteins that inhibit proteolytic enzymes, playing crucial roles in various biological processes such as blood coagulation, fibrinolysis, immune response, and tissue remodeling. Like other serpins, SERPINI2 regulates the activity of proteases by acting as a suicide substrate, forming a stable complex with the target protease, which leads to its irreversible inhibition. Although SERPINI2 is not as well-studied as other members of the serpin family, recent studies suggest that it is involved in the regulation of proteolysis in various tissues, with significant expression observed in pancreatic, hepatic, and other glandular tissues.
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