Serpin Family E Member 1 (SERPINE1) Antibody Pair
988€ (5 × 96 tests)
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Name
Serpin Family E Member 1 (SERPINE1) Antibody Pair
Category
Antibody Pairs
Provider
Abbexa
Reference
abx117515
Tested Applications
ELISA
Description
SERPINE1 Antibody Pair for use in Sandwich ELISA assay development.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Antibody Pairs |
| Immunogen Target | Serpin Family E Member 1 (SERPINE1) |
| Host | Capture Host: Rabbit Detection Host: Rabbit |
| Reactivity | Human, Guinea pig, Cow, Pig, Dog, Chicken, Goat |
| Assay Type | Sandwich |
| Clonality | Capture Clonality: Polyclonal Detection Clonality: Polyclonal |
| Conjugation | Biotin |
| Isotype | Capture Isotype: IgG Detection Isotype: IgG |
| Size 1 | 5 × 96 tests |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | PAI,PAI1,PAI-1,PLANH1,Plasminogen activator inhibitor 1,Endothelial plasminogen activator inhibitor,Serpin E1 |
| Background | Antibody pair for SERPINE1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
SERPINE1, also known as Plasminogen Activator Inhibitor-1 (PAI1), is a serine protease inhibitor that plays a key role in the regulation of fibrinolysis, the process that breaks down blood clots. It belongs to the serpin superfamily, which is a group of proteins involved in the inhibition of proteases. Specifically, SERPINE1 inhibits tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), both of which are enzymes responsible for converting plasminogen into plasmin, a protease that degrades fibrin, the main component of blood clots. The regulation of PAI-1 levels is crucial for maintaining the balance between clot formation and breakdown in the body. Abnormally high levels of PAI-1 are associated with thrombotic conditions, whereas deficiencies can lead to excessive bleeding.
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