Serpin Family B Member 2 (SERPINB2) Antibody
637€ (100 µl)
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Name
Serpin Family B Member 2 (SERPINB2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx115468
Tested Applications
ELISA, WB, IHC
Description
Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 2 Antibody is a Rabbit Polyclonal antibody against Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Serpin Family B Member 2 (SERPINB2) Immunogen: Human SERPINB2. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P05120 |
| Gene ID | 5055 |
| OMIM | 173390 |
| Alias | PAI,PAI2,PAI-2,PLANH2,HsT1201,Plasminogen activator inhibitor 2,Monocyte Arg-serpin,Placental plasminogen activator inhibitor,Serpin B2 |
| Background | Antibody anti-SERPINB2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
SERPINB2, also known as plasminogen activator inhibitor type 2 (PAI-2), is a member of the serine protease inhibitor (SERPIN) superfamily. This family of proteins is crucial for regulating proteolytic processes in various biological systems. Unlike its close relative PAI-1, which is primarily secreted into the extracellular space, SERPINB2 is predominantly found within the cytoplasm of cells, although it can also be secreted under certain conditions. SERPINB2 is encoded by the SERPINB2 gene located on chromosome 18q21.3 in humans. It is an acute-phase protein, meaning its expression is rapidly upregulated in response to inflammatory stimuli. SERPINB2 has been extensively studied due to its role in regulating fibrinolysis, the process by which blood clots are broken down. However, recent research has uncovered a broader range of functions for SERPINB2, including roles in immune regulation, apoptosis, and cellular differentiation
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