Serpin Family B Member 11 (gene/pseudogene) (SERPINB11) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
SERPINB11 Antibody is a Rabbit Polyclonal against SERPINB11.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Serpin Family B Member 11 (gene/pseudogene) (SERPINB11) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/2000 - 1/5000, WB: 1/500 - 1/2000, IHC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96P15 |
| Gene ID | 89778 |
| Alias | EPIPIN,SERPIN11,Serpin B11 |
| Background | Antibody anti-SERPINB11 |
| Status | RUO |
Descripción
SERPINB11 is a member of the serpin (serine protease inhibitor) superfamily, known for its role in regulating proteolytic processes. Unlike most serpins that inhibit proteases, SERPINB11 has unique features that set it apart from other family members. The serpin family plays a critical role in controlling protease activity across various biological pathways, such as inflammation, coagulation, apoptosis, and more. SERPINB11, specifically, is classified under the SERPINB subfamily, which predominantly operates in intracellular environments. This distinction highlights its potential for unique cellular functions in response to proteolytic stress and cellular damage. The SERPINB subgroup consists of serpins without signal peptides, localizing them primarily to the cytoplasm, unlike extracellular serpins, which have critical roles in blood coagulation and other extracellular processes
Related Products
Serpin Family B Member 11 (gene/pseudogene) (SERPINB11) Antibody
SerpinB11 is a serine proteinase inhibitor of the ovalbumin-like B clade of serpins. It was first discovered in human lung and prostate. Little is known about SerpinB11 tissue distribution and function. Splice variants of 305, 278 and 190 amino acids have been reported, with predicted masses of 33.97, 31.6 and 21.1 kDa respectively, and pIs of 8.11, 9.03 and 6.07 respectively. The 305 and 190 amino acid forms share the same aminoterminus as the 392 amino acid form. The 305 amino acid form has a deletion in residues 120-206, of the 392 amino acid form. The 190 amino acid form has a deletion in residues 57-259 relative to the long form. The 278 amino acid form starts at the third methionine, relative to the long form. All four forms contain the reactive center loop of the long form, but it is unknown if the shorter forms are active serpins. The predicted isoelectric points of SerpinB11 are significantly more basic than the other B clade serpins, and suggest a different localization or function for this serpin.
Ver Producto
Serpin Family B Member 11 (gene/pseudogene) (SERPINB11) Antibody
SERPINB11 Antibody is a Goat Polyclonal antibody against SERPINB11.
Ver Producto
Human Serpin B11 (SERPINB11) ELISA Kit
Human Serpin B11 (SERPINB11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Serpin B11 (SERPINB11) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto