Serpin D1 (SERPIND1) Antibody

Name: Serpin D1 (SERPIND1) Antibody
Brand: Abbexa
SKU: abx237750
Price: 364 EUR
Availability: OnlineOnly

Este producto es parte de SERPIND1 - serpin family D member 1

Pida mas información

935106861

info@markelab.com

Precio

364€ (100 µg)

Antibody anti-SERPIND1

proveedor

Abbexa

reference

abx237750

Tested Applications

ELISA, WB, IHC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

SERPIND1 Antibody is a Rabbit Polyclonal against SERPIND1.

Background

SERPIND1 encodes Heparin Cofactor II (HCII), a serine protease inhibitor (serpin) that plays a critical role in the regulation of coagulation. It shares functional similarities with antithrombin (SERPINC1), particularly in inhibiting thrombin, a key enzyme in the coagulation cascade. However, HCII exhibits a more specialized function as its activity is highly dependent on heparin-like glycosaminoglycans (GAGs), particularly dermatan sulfate, and to a lesser extent, heparin. HCII's involvement in thrombin inhibition and its activation through GAGs have made it an essential component in controlling clot formation and preventing thrombosis, particularly in vascular tissue. HCII deficiency has been linked to a predisposition for thromboembolic disorders and cardiovascular diseases.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

Serpin D1 (SERPIND1)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC

purity

≥ 95% (SDS-PAGE)

purification

Purified by immunogen affinity chromatography.

recommended dilution

WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.

size 1

100 µg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

SERPIND1

dry ice

availability

Shipped within 5-12 working days.

alias

HC2,LS2,HCF2,HCII,HLS2,THPH10,D22S673,Heparin cofactor 2,Heparin cofactor II,Protease inhibitor leuserpin-2,Serpin D1

uniprot id

https://www.uniprot.org/uniprotkb/P05546

gene id

https://www.ncbi.nlm.nih.gov/gene/3053

note

Concentration: 2 mg/ml - Validity: 12 months.

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reactivity

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status

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proveedor

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reference

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Tested Applications

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reactivity

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status

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