Serpin B8 (SERPINB8) Antibody
169€ (20 µg)
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name
Serpin B8 (SERPINB8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx302456
tested applications
ELISA, WB, IHC
Description
SERPINB8 Antibody is a Rabbit Polyclonal against SERPINB8.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Serpin B8 (SERPINB8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/200 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P50452 |
| Gene ID | 5271 |
| NCBI Accession | NP_001027018.1, NM_001031848.1, NP_001263419.1, NM_001276490.1, NP_002631.3, NM_002640.3 |
| OMIM | 601697 |
| Alias | PI8,CAP2,PI-8,PSS5,C18orf53,Serpin B8,Cytoplasmic antiproteinase 2,Peptidase inhibitor 8 |
| Background | Antibody anti-SERPINB8 |
| Status | RUO |
Descripción
SERPINB8 is part of the broader serine protease inhibitor (serpin) superfamily, which plays a crucial role in regulating protease activity within various physiological processes. This gene is located on chromosome 18q21.3 and encodes an intracellular protein that is primarily involved in inhibiting serine proteases, similar to other members of the SERPINB clade. The serpin superfamily is well-known for its diverse roles in cellular processes, including inflammation, coagulation, immune response, and apoptosis. SERPINB8, in particular, has been identified as an important player in several pathological conditions, especially those related to skin integrity and immune responses. Its expression is noted across multiple tissues, with significant roles in epithelial tissues such as the skin. The protein’s involvement in inflammatory skin diseases, along with its role in other cellular processes, makes it a critical subject of study in molecular biology and medicine.
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