Serpin B6 (SERPINB6) Antibody
312€ (60 µl)
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935106861
info@markelab.com
name
Serpin B6 (SERPINB6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx135864
tested applications
WB
Description
SERPINB6 Antibody is a Rabbit Polyclonal against SERPINB6.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Serpin B6 (SERPINB6) |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P35237 |
| Gene ID | 5269 |
| NCBI Accession | NP_004559.4 |
| Alias | CAP,PI6,PTI,PI-6,SPI3,DFNB91,MSTP057,Serpin B6,Cytoplasmic antiproteinase,Peptidase inhibitor 6,Placental thrombin inhibitor |
| Background | Antibody anti-SERPINB6 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
SERPINB6, a member of the serpin (serine protease inhibitor) superfamily, is a protein that plays a crucial role in protecting cells from the damaging effects of proteolysis, particularly in the inner ear and other tissues where protease activity must be tightly regulated. Unlike other serpins that inhibit extracellular proteases, SERPINB6 primarily functions within cells to protect against intracellular proteases, including those released during stress or injury. This protein is encoded by the SERPINB6 gene located on chromosome 6p25.2. SERPINB6 has garnered significant interest due to its implications in auditory protection and various pathological conditions, including hearing loss and certain neurodegenerative diseases.
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