Serpin B4 (SERPINB4) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Serpin B4 (SERPINB4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014873
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against SERPINB4 protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Serpin B4 (SERPINB4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P48594 |
| Alias | PI11,SCCA1,SCCA2,LEUPIN,SCCA-2,Serpin B4,Leupin,Peptidase inhibitor 11,Squamous cell carcinoma antigen 2 |
| Background | Antibody anti-SERPINB4 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
SERPINB4, also known as squamous cell carcinoma antigen 2 (SCCA2), is a member of the serine protease inhibitor (SERPIN) family, specifically part of the SERPINB clade. This protein is closely related to SERPINB3, with which it shares significant sequence homology and functional similarities. Like other members of the SERPIN superfamily, SERPINB4 plays a crucial role in regulating proteolytic processes within cells, which are essential for maintaining cellular homeostasis and responding to various physiological and pathological stimuli. SERPINB4 was initially identified in the context of squamous cell carcinoma (SCC), a common form of skin cancer, where it is often overexpressed alongside SERPINB3. The gene encoding SERPINB4 is located on chromosome 18q21, within a cluster of related SERPIN genes, including SERPINB3
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