Serpin B4 (SERPINB4) Antibody
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935106861
info@markelab.com
Precio
52€ (10 µg)
Antibody anti-SERPINB4
proveedor
Abbexareference
abx014873Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Rabbit polyclonal antibody against SERPINB4 protein. Immunogen region is Internal.
Background
SERPINB4, also known as squamous cell carcinoma antigen 2 (SCCA2), is a member of the serine protease inhibitor (SERPIN) family, specifically part of the SERPINB clade. This protein is closely related to SERPINB3, with which it shares significant sequence homology and functional similarities. Like other members of the SERPIN superfamily, SERPINB4 plays a crucial role in regulating proteolytic processes within cells, which are essential for maintaining cellular homeostasis and responding to various physiological and pathological stimuli. SERPINB4 was initially identified in the context of squamous cell carcinoma (SCC), a common form of skin cancer, where it is often overexpressed alongside SERPINB3. The gene encoding SERPINB4 is located on chromosome 18q21, within a cluster of related SERPIN genes, including SERPINB3
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Serpin B4 (SERPINB4)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
recommended dilution
WB: 1/500 - 1/3000, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
size 1
10 µg
size 2
100 µg
size 3
200 µg
size 4
300 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
SERPINB4
dry ice
No
availability
Shipped within 5-10 working days.
alias
PI11,SCCA1,SCCA2,LEUPIN,SCCA-2,Serpin B4,Leupin,Peptidase inhibitor 11,Squamous cell carcinoma antigen 2
uniprot id
note
Concentration: 1 mg/ml -
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