Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody

Este producto es parte de ACVR - Activin A Receptor Type
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416€ (200 µl)

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935106861
info@markelab.com
name
Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432278
tested applications
P-ELISA, WB

Description

Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody is a Goat Polyclonal antibody against Serine/threonine-Protein Kinase Receptor R3 (ACVRL1).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Serine/threonine-Protein Kinase Receptor R3 (ACVRL1)
Host
Goat
Reactivity
Human
Recommended Dilution
P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA, WB
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
94
NCBI Accession
NP_000011.2, NP_001070869.1
Alias
Activin receptor-like kinase 1,ALK-1,SKR3
Background
Antibody anti-ACVRL1
Status
RUO
Note
Concentration: 0.5 mg/ml -

Descripción

ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.

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