Name: Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody
Brand: Abbexa
SKU: abx432278
Price: 387.5 EUR
Availability: OnlineOnly

Background

ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Serine/threonine-Protein Kinase Receptor R3 (ACVRL1)

host

Goat

conjugation

Unconjugated

form

Liquid

tested applications

P-ELISA, WB

purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

buffer

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.

size 1

200 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

ACVRL1

dry ice

availability

Shipped within 1-3 working days.

alias

Activin receptor-like kinase 1,ALK-1,SKR3

gene id

https://www.ncbi.nlm.nih.gov/gene/94

NCBI accession

NP_000011.2, NP_001070869.1

note

This product is for research use only.

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anti- ACVRL1 antibody

proveedor

FineTest

reference

FNab00131

Tested Applications

ELISA, WB, IHC, FC, IP

reactivity

human

status

RUO

clonality

polyclonal

Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel developme...

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