Serine/threonine-Protein Kinase LMTK1 (LMTK1) Antibody
351€ (100 µg)
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935106861
info@markelab.com
name
Serine/threonine-Protein Kinase LMTK1 (LMTK1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx375399
tested applications
ELISA, WB
Description
Serine/threonine-Protein Kinase LMTK1 (LMTK1) Antibody is a Rabbit Polyclonal antibody against Serine/threonine-Protein Kinase LMTK1 (LMTK1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Serine/threonine-Protein Kinase LMTK1 (LMTK1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6ZMQ8 |
| Gene ID | 9625 |
| Alias | AATYK,AATYK1,LMR1,LMTK1,PPP1R77,P35bp,AATK |
| Background | Antibody anti-AATK |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
AATK (Apoptosis-Associated Tyrosine Kinase), also known as LMTK1 (Lemur Tyrosine Kinase 1), is a member of the serine/threonine-protein kinase family. PTKs (Protein Tyrosine Kinases) facilitate the transfer of the gamma-phosphoryl group from ATP to tyrosine (Tyr) residues. LMTK1, also known as Apoptosis-associated tyrosine kinase (AATK) or AATYK, is a cytoplasmic kinase with an extensive C-terminal region. The expression of LMTK1 is elevated during growth arrest and apoptosis in myeloid cells . LMTK1 is implicated in neural differentiation and serves as a regulator for the Na-K-2Cl cotransporter, a membrane protein involved in cell proliferation, survival, epithelial transport, and blood pressure control. The protein comprises a tyrosine kinase domain at the N-terminal end and a proline-rich domain at the C-terminal end. Studies on the mouse homologue suggest its potential role in inducing growth arrest and apoptosis in myeloid precursor cells. Additionally, it may play a part in promoting differentiation in neuronal cells . Recent reports also highlight its suppressive effect on melanoma development
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