Serine/threonine-Protein Kinase BRSK1 (BRSK1) Antibody (HRP)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
BRSK1 Antibody (HRP) is a Rabbit Polyclonal against BRSK1 conjugated to HRP.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Serine/threonine-Protein Kinase BRSK1 (BRSK1) Immunogen: Recombinant Human Serine/threonine-protein kinase BRSK1 protein (426-591AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8TDC3 |
| Gene ID | 84446 |
| NCBI Accession | NP_115806.1, NM_032430.1 |
| OMIM | 609235 |
| Background | Antibody anti-BRSK1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Related Products
BRSK1 antibody
Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Thr-529' and 'Ser-579'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1. Also acts as a positive regulator of centrosome duplication by mediating phosphorylation of gamma-tubulin(TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins to the centrosome. Involved in the UV-induced DNA damage checkpoint response, probably by inhibiting CDK1 activity through phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25C.
Ver Producto
Serine/threonine-Protein Kinase BRSK1 (BRSK1) Antibody
Rabbit polyclonal antibody against BRSK1 protein. Immunogen region is Internal.
Ver Producto
Serine/threonine-Protein Kinase BRSK1 (BRSK1) Antibody
Br Serine/Threonine Kinase 1 Antibody is a Rabbit Polyclonal antibody against Br Serine/Threonine Kinase 1.
Ver Producto