Semaphorin-3C (SEMA3C) Antibody
169€ (20 µg)
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935106861
info@markelab.com
name
Semaphorin-3C (SEMA3C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx348747
tested applications
ELISA, IHC
Description
Semaphorin-3C (SEMA3C) Antibody is a Rabbit Polyclonal antibody for the detection of Human SEMA3C.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Semaphorin-3C (SEMA3C) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99985 |
| Gene ID | 10512 |
| OMIM | 602645 |
| Alias | SemE,SEMAE,Semaphorin-E |
| Background | Antibody anti-SEMA3C |
| Status | RUO |
Descripción
SEMA3C (Semaphorin 3C) is another key member of the class 3 semaphorins, primarily involved in neuronal pathfinding, cardiovascular development, and cancer biology. SEMA3C signals through neuropilin-2 (NRP2) and plexin receptors to regulate cellular behaviors such as migration, invasion, and adhesion. In cancer, SEMA3C is frequently upregulated, where it promotes tumor growth and metastasis by facilitating angiogenesis and modulating the tumor microenvironment. Its dual roles in development and oncogenesis make it a compelling target for both regenerative medicine and oncology.
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