Semaphorin 3C (SEMA3C) Antibody
637€ (100 µl)
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935106861
info@markelab.com
name
Semaphorin 3C (SEMA3C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx116904
tested applications
ELISA, WB
Description
Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C Polyclonal Antibody is a Rabbit Polyclonal antibody against Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C Polyclonal Antibody.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Semaphorin 3C (SEMA3C) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99985 |
| Gene ID | 10512 |
| NCBI Accession | NP_006370.1, NM_006379.3 |
| OMIM | 602645 |
| Alias | SemE,SEMAE,Semaphorin-E |
| Background | Antibody anti-SEMA3C |
| Status | RUO |
Descripción
SEMA3C (Semaphorin 3C) is another key member of the class 3 semaphorins, primarily involved in neuronal pathfinding, cardiovascular development, and cancer biology. SEMA3C signals through neuropilin-2 (NRP2) and plexin receptors to regulate cellular behaviors such as migration, invasion, and adhesion. In cancer, SEMA3C is frequently upregulated, where it promotes tumor growth and metastasis by facilitating angiogenesis and modulating the tumor microenvironment. Its dual roles in development and oncogenesis make it a compelling target for both regenerative medicine and oncology.
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