Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163) Antibody (FITC)

Este producto es parte de CD163 - CD163 molecule
Product Graph
169€ (20 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx107317

Description

Scavenger receptor cysteine-rich type 1 protein M130 Antibody (FITC) is a Rabbit Polyclonal antibody against Scavenger receptor cysteine-rich type 1 protein M130 conjugated to FITC.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163)
Host
Rabbit
Reactivity
Mouse
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
FITC
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q2VLH6
Gene ID
93671
NCBI Accession
NP_444324.2, NM_053094.2
Alias
Scavenger receptor cysteine-rich type 1 protein M130,M130,MM130,SCARI1,Hemoglobin scavenger receptor
Background
Antibody anti-CD163
Status
RUO

Descripción

CD163, also known as the hemoglobin scavenger receptor, is a transmembrane glycoprotein expressed primarily on the surface of monocytes and macrophages. Encoded by the CD163 gene on chromosome 12 in humans, CD163 functions as a receptor for the haptoglobin-hemoglobin (Hp-Hb) complex. It is critical in scavenging free hemoglobin (Hb) released during red blood cell breakdown, thus protecting tissues from oxidative damage and inflammation due to free hemoglobin. Additionally, CD163 is part of the cysteine-rich scavenger receptor family and plays an important role in immune modulation, inflammation resolution, and tissue remodeling. Through its function as an anti-inflammatory receptor, CD163 contributes to the regulation of immune responses, often acting as a “sensor” for inflammatory conditions. When inflammation is detected, CD163-expressing cells can trigger responses that help protect tissues, making this molecule an essential component in maintaining immune homeostasis and limiting excessive immune reactions.

Related Products

APC-30123

APC Anti-Mouse CD163 (S15049F)

Ver Producto
EH0075

Human sCD163 (Soluble Cluster of Differentiation 163) ELISA Kit

Ver Producto
EM1475

Mouse sCD163 (Soluble Cluster of Differentiation 163) ELISA Kit

Ver Producto