Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163) Antibody

Este producto es parte de CD163 - CD163 molecule
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442€ (100 µg)

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935106861
info@markelab.com
name
Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx414019
tested applications
WB, IHC, IF/ICC, FCM, IP

Description

Cluster of Differentiation 163 (CD163) Antibody is a Mouse Monoclonal antibody against Cluster of Differentiation 163 (CD163).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163)
Host
Mouse
Reactivity
Pig
Recommended Dilution
Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Purification
Purified
Size 1
100 µg
Form
Liquid
Tested Applications
WB, IHC, IF/ICC, FCM, IP
Buffer
PBS. Contains sodium azide.
Availability
Shipped within 3-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q2VL90
Alias
Scavenger receptor cysteine-rich type 1 protein M130,M130,MM130,SCARI1,Hemoglobin scavenger receptor
Background
Antibody anti-CD163
Status
RUO
Note
Concentration: 1.0 mg/ml - 

Descripción

CD163, also known as the hemoglobin scavenger receptor, is a transmembrane glycoprotein expressed primarily on the surface of monocytes and macrophages. Encoded by the CD163 gene on chromosome 12 in humans, CD163 functions as a receptor for the haptoglobin-hemoglobin (Hp-Hb) complex. It is critical in scavenging free hemoglobin (Hb) released during red blood cell breakdown, thus protecting tissues from oxidative damage and inflammation due to free hemoglobin. Additionally, CD163 is part of the cysteine-rich scavenger receptor family and plays an important role in immune modulation, inflammation resolution, and tissue remodeling. Through its function as an anti-inflammatory receptor, CD163 contributes to the regulation of immune responses, often acting as a “sensor” for inflammatory conditions. When inflammation is detected, CD163-expressing cells can trigger responses that help protect tissues, making this molecule an essential component in maintaining immune homeostasis and limiting excessive immune reactions.

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