SARS-CoV-2 Spike NTD Antibody

Descripción

SARS-CoV-2/COVID-19 Spike NTD Antibody is a chimaeric recombinant antibody expressed in CHO cells against SARS-CoV-2 Spike N-Terminal Domain Protein, containing Mouse variable region and Human IgG constant region. The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.