RNA Polymerase III Subunit G (POLR3G) Antibody

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Description
RNA Polymerase III Subunit G (POLR3G) Antibody is a Rabbit Polyclonal antibody against RNA Polymerase III Subunit G (POLR3G).
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | RNA Polymerase III Subunit G (POLR3G) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | Validated in IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Purification | Purified by affinity chromatography using epitope-specific immunogen. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O15318 |
Gene ID | 10622 |
Background | Antibody anti-POLR3G |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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POLR3G antibody
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the RPC3/POLR3C-RPC6/POLR3F-RPC7/POLR3G subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
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RNA Polymerase III Subunit G (POLR3G) Antibody
POLR3G Antibody is a Rabbit Polyclonal against POLR3G.
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RNA Polymerase III Subunit G (POLR3G) Antibody
POLR3G Antibody is a Rabbit Polyclonal against POLR3G.
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