RNA Binding Motif Protein 15 (RBM15) Antibody

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Description
RBM15 Antibody is a Rabbit Polyclonal antibody against RBM15. Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | RNA Binding Motif Protein 15 (RBM15) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | WB |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q96T37 |
Gene ID | 64783 |
NCBI Accession | NP_001188474.1 |
Background | Antibody anti-RBM15 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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RBM15 antibody
May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.
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RBM15 antibody
May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.
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