Blood Group RhD Polypeptide (RHD) Antibody
221€ (50 µg)
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Name
Blood Group RhD Polypeptide (RHD) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx323345
Tested Applications
ELISA, WB
Description
Blood Group RhD Polypeptide (RHD) is a Rabbit Polyclonal against RHD.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Blood Group RhD Polypeptide (RHD) Immunogen: Synthesized peptide derived from the Internal region of human CD240d. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q02161 |
| Gene ID | 6007 |
| Alias | Blood group Rh(D) polypeptide,RH,Rh4,RH30,RhII,RhPI,DIIIc,RHCED,RHDel,RHPII,RhDCw,CD240D,Rh polypeptide 2,Rhesus D antigen |
| Background | Antibody anti-RHD |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RHD (Rh blood group D antigen), encoded by the RHD gene, is a major component of the Rh blood group system, one of the most clinically significant blood group systems in humans. The Rh system includes a range of antigens, but the D antigen is the most important for its role in blood transfusion compatibility, pregnancy, and disease. The Rh system is widely recognized in transfusion medicine, where the presence or absence of the D antigen determines whether an individual is classified as Rh-positive (Rh+) or Rh-negative (Rh-). The Rh system, particularly the D antigen, plays a crucial role in immune reactions, alloimmunization, and hemolytic disease of the newborn (HDN). The RHD gene is located on chromosome 1 and is closely linked to the RHCE gene, which encodes other Rh antigens, particularly C and E. The Rh proteins, including the D antigen, are integral membrane proteins that span the cell membrane and play an essential role in the transportation of ions and gases across the cell membrane, especially in erythrocytes (red blood cells). The RHD gene codes for the RhD protein, and its expression is key to determining whether an individual expresses the RhD antigen on the surface of their erythrocytes.
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