Retinoic Acid Early-Inducible Protein 1-Epsilon (RAET1E) Antibody
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Description
Retinoic Acid Early-Inducible Protein 1-Epsilon (RAET1E) Antibody is a Rabbit polyclonal antibody for the detection of Mouse Retinoic Acid Early-Inducible Protein 1-Epsilon (RAET1E).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Retinoic Acid Early-Inducible Protein 1-Epsilon (RAET1E) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9CZQ6 |
| Gene ID | 379043 |
| NCBI Accession | NP_937836.1 |
| Background | Antibody anti-RAET1E |
| Status | RUO |
Descripción
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Members of the RAET1 family, such as RAET1E, are major histocompatibility complex (MHC) class I-related genes located within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E and RAET1G (MIM 609244) differ from the other RAET1 proteins (e.g., RAET1I, or ULBP1; MIM 605697) in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. RAET1E is a ligand for NKG2D (KLRK1; MIM 611817), which is expressed on the surface of several types of immune cells and is involved in innate and adaptive immune responses (summary by Radosavljevic et al. (2002) [PubMed 11827464] and Cao et al. (2007) [PubMed 17470428]).
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