Renin Receptor (ATP6AP2) Antibody
260€ (50 µg)
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name
Renin Receptor (ATP6AP2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx377013
tested applications
ELISA, WB, IHC
Description
Renin Receptor (ATP6AP2) Antibody is a Rabbit polyclonal antibody for the detection of Human Renin Receptor (ATP6AP2).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Renin Receptor (ATP6AP2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75787 |
| Gene ID | 10159 |
| NCBI Accession | NP_005756.2 |
| Background | Antibody anti-ATP6AP2 |
| Status | RUO |
Descripción
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ATP6AP2, also named as ATP6IP2, CAPER, ELDF10, N14F, ATP6M8-9, Renin receptor and prorenin receptor, is believed to potentiate the renin–angiotensin system(RAS), conferring to prorenin, a likely pathological role at tissue level. The PRR has been identified in the microvascular endothelial cells of the retina, in which it seems to be involved in pathological neovascularization processes. The present study demonstrates for the first time that the PRR is expressed in human ATP6AP2 and suggests a molecular mechanism by which hypertension may exacerbate the pathology of dry AMD.
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