Regulator Of G Protein Signaling 2 (RGS2) Antibody (HRP)

169€ (20 µg)
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935106861
info@markelab.com
name
Regulator Of G Protein Signaling 2 (RGS2) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx305112
tested applications
ELISA
Description
RGS2 Antibody (HRP) is a Rabbit Polyclonal against RGS2 conjugated to HRP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Regulator Of G Protein Signaling 2 (RGS2) Immunogen: Recombinant human Regulator of G-protein signaling 2 protein (1-211AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P41220 |
| Gene ID | 5997 |
| NCBI Accession | NP_002914.1, NM_002923.3 |
| OMIM | 600861 |
| Background | Antibody anti-RGS2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle(By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein(PubMed:19736320).
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