Reelin (RELN) Antibody
169€ (20 µg)
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name
Reelin (RELN) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx110643
tested applications
ELISA, IHC
Description
Reelin Antibody is a Rabbit Polyclonal antibody against Reelin. Recombinant Human Reelin ProteinExtracellular Matrix Serine Protease That Plays A Role In Layering Of Neurons In The Cerebral Cortex And CerebellumRegulates Microtubule Function In Neurons And Neuronal MigRationAffects MigRation Of Sympathetic Preganglionic Neurons In The Spinal Cord, Where It Seems To Act As A Barrier To Neuronal MigRationEnzymatic Activity Is Important For The Modulation Of Cell AdhesionBinding To The Extracellular Domains Of Lipoprotein Receptors Vldlr And Lrp8/Apoer2 Induces Tyrosine Phosphorylation Of Dab1 And Modulation Of Tau Phosphorylation.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Reelin (RELN) Immunogen: Recombinant Human Reelin protein (26-254AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P78509 |
| Gene ID | 5649 |
| NCBI Accession | NP_005036.2, NM_005045.3 |
| OMIM | 257320 |
| Background | Antibody anti-RELN |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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RELN antibody
Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation(By similarity).
Ver Producto