Recombinant Human HSP90B1

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935106861
info@markelab.com
name
Recombinant Human HSP90B1
category
Proteins and Peptides
provider
FineTest
reference
P0700
tested applications
Western Blot, ELISA

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Host
E.Coli
Reactivity
Human
Assay Data
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Observed MW
35.7 kDa
Expression
282-409
Purity
Greater than 90% as determined by SDS-PAGE.
Size 1
50μg
Size 2
200μg
Size 3
1mg
Form
Lyophilized powder
Tested Applications
Western Blot, ELISA
Buffer
Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5% trehalose, pH 7.4.
Availability
7 days
Storage
The lyophilized protein is stable at -20 °C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 °C for 3 months or 1 week at 2 to 8 °C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle.
UniProt ID
P14625
Alias
ECGP, Endoplasmin, GP96, gp96 homolog, GRP 94, GRP94, HSP90B1, TRA1, Tumor rejection antigen 1
Background
Protein HSP90B1
Status
RUO
Note
Tag : N-terminal His-IF2DI Tag

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HSP90 proteins are highly conserved molecular chaperones, which normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1(GP96 or GRP94) is an endoplasmic reticulum paralogue of the cytosolic HSP90. As a major ER chaperone to mediate the UPR and a master chaperone for Toll-like receptors(TLRs), HSP90b1 chaperones peptides to MHC class I molecules of dendritic cells and other antigen-presenting cells, as well as facilitating the assembly of immunoglobulin. The protein is also involved in many other bio-processes. This antibody was generated against the C-terminal region of full-length HSP90b1.

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