Recombinant Human CIDEA
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | 1-219 |
| Host | E.Coli |
| Origin | Human |
| Observed MW | 45.3 kDa |
| Expression | Recombinant |
| Purity | Greater than 85% by SDS-PAGE gel analyses |
| Purification | N-terminal His-IF2DI Tag |
| Size 1 | 50μg |
| Size 2 | 200μg |
| Size 3 | 1mg |
| Form | Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose and 0.06% proclin, pH7.4 |
| Tested Applications | Western Blot, ELISA |
| Buffer | Centrifuge the vial at 10,000 rpm for 1 minute, reconstitute at 200 μg/ml in Reconstitute with Sterile distilled water |
| Availability | 3-4 weeks |
| Storage | -20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution |
| UniProt ID | O60543 |
| Alias | CIDE-A, cell death-inducing DFFA-like effector a, cell death inducing DFFA like effector a,CIDEA |
| Background | Proteins CIDEA |
| Status | RUO |
| Note | This product is for research use only. |
CIDEA is a lipid droplet-associated protein involved in regulating lipid metabolism and energy homeostasis. It promotes lipid droplet fusion and inhibits lipolysis by modulating the activity of key enzymes such as adipose triglyceride lipase (ATGL). CIDEA is highly expressed in brown adipose tissue, where it contributes to thermogenesis and energy expenditure. Beyond its metabolic functions, CIDEA also plays a role in apoptosis, where it interacts with caspase-activated DNAse to mediate DNA fragmentation. Dysregulation of CIDEA is associated with obesity, insulin resistance, and non-alcoholic fatty liver disease. Research on CIDEA focuses on its dual roles in lipid metabolism and apoptosis, offering potential therapeutic targets for metabolic disorders and cancer.
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