Recombinant Human ADA

Este producto es parte de ADA - Adenosine Deaminase
Recombinant Human ADA

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Proteins ADA

proveedor

FineTest

reference

P4379

Tested Applications

Western Blot,ELISA

reactivity

status

RUO

clonality


Background

Adenosine deaminase (ADA) is an enzyme crucial in purine metabolism, responsible for catalyzing the irreversible deamination of adenosine and deoxyadenosine to inosine and deoxyinosine, respectively. ADA is predominantly found in lymphocytes, with high activity in tissues such as the thymus, spleen, and bone marrow. It is vital for the development and maintenance of the immune system, as its deficiency leads to the accumulation of toxic purine metabolites, which impair DNA synthesis and lymphocyte survival. Mutations in the ADA gene result in severe combined immunodeficiency (SCID), characterized by a lack of functional T, B, and NK cells. ADA is also widely studied as a marker of immune activation and inflammation in conditions like tuberculosis and rheumatoid arthritis. Therapeutic interventions for ADA deficiency include enzyme replacement therapy and gene therapy, both of which aim to restore immune function.

Características del producto

category

Proteins and Peptides


origin

Human


host

E.Coli


immunogen target

1-363


host

E.Coli


form

Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4


tested applications

Western Blot,ELISA


size 1

50μg


size 2

200μg


size 3

1mg


observerd MW

39.8 kDa


expression

Recombinant


purity

Greater than 95% by SDS-PAGE gel analyses


purification

His tag


buffer

Reconstitute with Sterile distilled water


storage

-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution


or code

ADA


availability

3-4 weeks


alias

Adenosine aminohydrolase


note

This product is for research use only.


Quizá le pueda interesar

Human ADA(Adenosine deaminase) ELISA Kit

Human ADA(Adenosine deaminase) ELISA Kit

proveedor

FineTest

reference

EH1544

reactivity

human

status

RUO

Precio a consultar

Ver más

Mouse ADA(Adenosine deaminase) ELISA Kit

Mouse ADA(Adenosine deaminase) ELISA Kit

proveedor

FineTest

reference

EM1599

reactivity

mouse

status

RUO

Precio a consultar

Ver más

Rat ADA(Adenosine deaminase) ELISA Kit

Rat ADA(Adenosine deaminase) ELISA Kit

proveedor

FineTest

reference

ER1974

reactivity

rat

status

RUO

Precio a consultar

Ver más