Recombinant Human ACTA2

Este producto es parte de ACTA2 - Actin alpha 2 smooth muscle
Recombinant Human ACTA2

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935106861

info@markelab.com

Precio

Precio a consultar

Proteins ACTA2

proveedor

FineTest

reference

P0747

Tested Applications

Western Blot, ELISA

reactivity

status

RUO

clonality


Background

ACTA2 encodes actin alpha 2, a protein that is a key component of the contractile apparatus in smooth muscle cells. Smooth muscle alpha actin is a major component of the contractile apparatus in smooth muscle cells, contributing to the contractility and mechanical properties of various organs and tissues, including blood vessels, airways, and the gastrointestinal tract. ACTA2 (as with all the actins) is extremely highly conserved and found in nearly all mammals Is essential for physiological processes such as blood pressure regulation, airway tone, and peristalsis in the digestive system. It forms filamentous structures that interact with other proteins to generate force and facilitate muscle contraction. Various signaling pathways and transcription factors control the expression of ACTA2, ensuring its proper expression in smooth muscle cells. Mutations or dysregulation of ACTA2 expression have been associated with several smooth muscle-related disorders, including vascular diseases such as thoracic aortic aneurysms and dissections (TAAD), familial thoracic aortic aneurysms and dissections (FTAAD), and other vascular malformations.

Características del producto

category

Proteins and Peptides


origin

Human


host

E.Coli


immunogen target

3-100


host

E.Coli


form

Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4


tested applications

Western Blot, ELISA


size 1

50μg


size 2

200μg


size 3

1mg


observerd MW

31.4 KDa


expression

Recombinant


purity

Greater than 95% by SDS-PAGE gel analyses


purification

IF2DI tag


buffer

Reconstitute with Sterile distilled water


storage

-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution


or code

ACTA2


availability

7 days


alias

ACTSA,α-SMA


note

This product is for research use only.


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anti- ACTA2/smooth muscle actin antibody

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status

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clonality

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