Receptor Tyrosine-Protein Kinase Erbb-4 (ERBB4) Antibody

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312€ (50 µg)

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935106861
info@markelab.com
name
Receptor Tyrosine-Protein Kinase Erbb-4 (ERBB4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx421117
tested applications
FCM

Description

Receptor Tyrosine-Protein Kinase Erbb-4 (ERBB4) Antibody is a Mouse Monoclonal antibody for the detection of Receptor Tyrosine-Protein Kinase Erbb-4 (ERBB4) in Human samples.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Receptor Tyrosine-Protein Kinase Erbb-4 (ERBB4)
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG2a
Clone ID
B121
Purity
> 95%
Purification
Purified by Protein A/G affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
FCM
Buffer
0.01 M PBS, pH 7.4.
Availability
Shipped within 5-12 working days.
Storage
Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles.
Dry Ice
No
UniProt ID
Q15303
Gene ID
2066
NCBI Accession
NP_001036064.1
Background
Antibody anti-ERBB4
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

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This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

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