Receptor Tyrosine Kinase Like Orphan Receptor 2 (ROR2) Antibody
286€ (100 µl)
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Name
Receptor Tyrosine Kinase Like Orphan Receptor 2 (ROR2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx128158
Tested Applications
WB, IHC
Description
Receptor Tyrosine Kinase Like Orphan Receptor 2 Antibody is a Rabbit Polyclonal against Receptor Tyrosine Kinase Like Orphan Receptor 2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Receptor Tyrosine Kinase Like Orphan Receptor 2 (ROR2) Immunogen: ROR2 (Trp683-Val934) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | BDB,BDB1,NTRKR2,Neurotrophic tyrosine kinase, receptor-related 2,Tyrosine-protein kinase transmembrane receptor ROR2 |
| Background | Antibody anti-ROR2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2) is closely related to ROR1 but has distinct functions, particularly in skeletal and cardiovascular development. ROR2 acts as a coreceptor for Wnt5a in the planar cell polarity pathway, essential for cell movement and polarity during embryogenesis. Mutations in the ROR2 gene have been associated with Robinow syndrome and brachydactyly type B, which are developmental disorders affecting skeletal and facial structures. ROR2 is also implicated in cancer biology, where its expression correlates with aggressive tumor behaviors, including invasion and metastasis. Its dual roles in development and disease make ROR2 a critical player in both developmental biology and oncology research.
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