Rat Vitamin D Receptor (VDR) CLIA Kit
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Description
Rat Vitamin D Receptor (VDR) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
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Product specifications
| Category | CLIA Kits |
| Immunogen Target | Vitamin D Receptor (VDR) |
| Reactivity | Rat |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.625 ng/ml - 40 ng/ml |
| Sensitivity | < 0.244 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | NR1I1,PPP1R163,Vitamin D3 receptor,1,25-dihydroxyvitamin D3 receptor,Nuclear receptor subfamily 1 group I member 1 |
| Background | CLIA Kits VDR |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Vitamin D receptor (VDR) is a nuclear receptor that mediates the effects of vitamin D, a crucial nutrient involved in calcium and phosphate homeostasis, bone health, immune function, and cellular growth VDR is activated upon binding to the active form of vitamin D, calcitriol, which allows it to regulate gene expression by binding to vitamin D response elements (VDREs) in target genes VDR is involved in regulating calcium absorption in the intestine, bone mineralization, and the modulation of immune responses, particularly in regulating inflammation and the function of T cells It also plays a role in the prevention of certain cancers, cardiovascular diseases, and autoimmune disorders Dysregulation of VDR activity has been linked to diseases such as osteoporosis, rickets, cardiovascular disease, and cancer In addition, VDR is a target for therapies aimed at managing conditions related to vitamin D deficiency, autoimmune diseases, and bone disorders
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