Rat Vasopressin V1b receptor (AVPR1B) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for AVPR1B
proveedor
Abbexareference
abx256670Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Vasopressin V1b receptor (AVPR1B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Vasopressin V1b Receptor (AVPR1B) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
AVPR1B is a G protein-coupled receptor that binds the hormone arginine vasopressin (AVP), a key regulator of water balance, blood pressure, and social behaviors. This receptor is primarily expressed in the anterior pituitary, where it plays an important role in the secretion of ACTH (adrenocorticotropic hormone) in response to stress. AVPR1B also plays a role in regulating behaviors associated with the stress response, including anxiety and social interactions. Upon activation, AVPR1B couples to Gq proteins, stimulating phospholipase C (PLC) and increasing intracellular calcium, leading to the release of ACTH from the pituitary gland. Dysregulation of AVPR1B is associated with stress-related disorders, such as anxiety and depression, and alterations in AVPR1B signaling have been implicated in diseases such as Cushing's syndrome and some forms of neuroendocrine tumors. Targeting AVPR1B with antagonists is being explored for the treatment of stress-related diseases and disorders linked to excessive ACTH secretion.
Características del producto
category
ELISA Kits
immunogen target
Vasopressin V1b receptor (AVPR1B)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
AVPR1B,Antidiuretic hormone receptor 1b,AVPR3,V3,V1bR,Vasopressin V3 receptor,VPR3,vasopressin V1b receptor,V3/V1b pituitary vasopressin receptor,V1bR,VPR3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AVPR1B
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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PolyclonalThe protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-...
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