Rat Vascular endothelial growth factor receptor 2 / FLK1 (KDR) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits KDR
proveedor
Abbexareference
abx156224Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Vascular endothelial growth factor receptor 2 / FLK1 (KDR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Vascular endothelial growth factor receptor 2 / FLK1 (KDR) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)No significant cross-reactivity or interference between Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) and analogues was observed.
Background
KDR, also known as vascular endothelial growth factor receptor 2 (VEGFR-2), is a critical protein in the regulation of angiogenesis and vascular development. This receptor tyrosine kinase (RTK) is encoded by the KDR gene located on chromosome 4q12 in humans. KDR is a member of the VEGF receptor family, which plays an essential role in the processes of vasculogenesis and angiogenesis by mediating the cellular responses to the vascular endothelial growth factor (VEGF). The VEGF family consists of several ligands, with VEGF-A being the primary ligand for KDR. KDR is predominantly expressed in endothelial cells, where it regulates vascular permeability, endothelial cell proliferation, migration, and survival. Due to its pivotal role in vascular biology, KDR has been extensively studied in the context of cancer, where angiogenesis is a crucial process for tumor growth and metastasis. KDR's involvement in pathological angiogenesis makes it a significant target for anti-angiogenic therapies in cancer treatment. Moreover, it has implications in other diseases characterized by abnormal vascular growth, such as age-related macular degeneration and rheumatoid arthritis.
Características del producto
category
ELISA Kits
immunogen target
Vascular endothelial growth factor receptor 2 / FLK1 (KDR)
reactivity
Rat
test range
62.5 pg/ml - 4000 pg/ml
sensitivity
< 24.7 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
FLK1,CD309,VEGFR,VEGFR2,VEGFR-2,Protein-tyrosine kinase receptor flk-1,Fetal liver kinase 1,Vascular endothelial growth factor receptor 2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
KDR
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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