rat TSC1 (pT417) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
rat TSC1 (pT417) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx032239
tested applications
ELISA, DB
Description
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: TSC1 (pT417) Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T417 of rat TSC1. |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 129 kDa |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, DB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Z136 |
| Background | Antibody anti-TSC1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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