Rat Transmembrane Emp24-Domain Containing Protein 1 (TMED1) ELISA Kit
611€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Transmembrane Emp24-Domain Containing Protein 1 (TMED1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx353993
tested applications
ELISA
Description
Rat Transmembrane Emp24-Domain Containing Protein 1 (TMED1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Transmembrane Emp24-Domain Containing Protein 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Transmembrane Emp24-Domain Containing Protein 1 (TMED1) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | 0.1 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5BK85 |
| Gene ID | 315461 |
| Alias | TMED1,IL1RL1LG,IL1RL1L,Tp24; p24g1 |
| Background | Elisa Kits for: TMED1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
TMED1, a member of the p24 protein family, is a type I transmembrane protein involved in vesicular trafficking, particularly in the early secretory pathway. TMED1 localizes to the endoplasmic reticulum (ER), ER-Golgi intermediate compartment (ERGIC), and the Golgi apparatus, where it regulates the transport and sorting of cargo proteins between cellular compartments. It interacts with coat protein complexes (COPI and COPII) to facilitate vesicle budding, cargo selection, and trafficking efficiency. TMED1 also plays a role in cellular signaling and homeostasis through its interaction with membrane-bound receptors and secretory proteins. It is widely expressed in various tissues, particularly in secretory cells and immune tissues, where it supports protein maturation, secretion, and immune regulation. Dysregulation of TMED1 has been linked to cancers and immune dysfunction, where altered trafficking pathways impair protein sorting and cellular communication. Knockdown studies show defects in vesicle formation, impaired protein transport, and disrupted Golgi integrity, emphasizing its role in maintaining secretory pathway dynamics, intracellular signaling, and cellular homeostasis.
Related Products
Recombinant Human TMED1
Ver Producto
Transmembrane Emp24-Domain Containing Protein 1 (TMED1) Antibody
The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1). This protein lacks any similarity to other interleukin 1 ligands. The functional significance of its interaction with IL1RL1 is not known.
Ver Producto
Transmembrane Emp24-Domain Containing Protein 1 (TMED1) Antibody
TMED1 Antibody is a Rabbit Polyclonal against TMED1.
Ver Producto