Rat TRAF3 Interacting Protein 1 (TRAF3IP1) ELISA Kit
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Description
Rat TRAF3 Interacting Protein 1 (TRAF3IP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat TRAF3-interacting protein 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | TRAF3 Interacting Protein 1 (TRAF3IP1) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5XIN3 |
| Alias | IFT54, MIPT3,Interleukin-13 receptor alpha 1-binding protein 1,Intraflagellar transport protein 54 homolog, CFAP116, FAP116, IFT54, MIP-T3, SLSN9 |
| Background | Elisa kits for TRAF3IP1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
TRAF3IP1, also known as IFT54, is a signaling adaptor protein that interacts with TRAF3 and participates in immune signaling and intracellular transport processes. It is a critical component of the intraflagellar transport (IFT) machinery, which regulates ciliogenesis and ciliary signaling pathways by mediating the transport of cargo proteins within primary cilia. TRAF3IP1 plays a key role in developmental processes, cell signaling, and tissue homeostasis by facilitating cilia assembly and function. It is expressed in ciliated epithelial tissues, immune cells, and the brain, where it regulates processes such as Hedgehog signaling, immune response, and cytoskeletal organization. Dysregulation or mutations in TRAF3IP1 are associated with ciliopathies, including Joubert syndrome and nephronophthisis, due to defective cilia function and signaling. Knockout studies reveal impaired ciliogenesis, disrupted signaling pathways, and developmental abnormalities, emphasizing its essential role in cilia-mediated signaling and cellular organization.
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