Rat Tissue Factor Pathway Inhibitor (TFPI) Protein

Pida mas información
935106861
info@markelab.com
Precio
182€ (10 µg)
Protein TFPI
proveedor
Abbexareference
abx069319Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Tissue Factor Pathway Inhibitor (TFPI) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Background
Tissue Factor Pathway Inhibitor (TFPI) is a crucial regulator of the extrinsic coagulation cascade, primarily inhibiting the tissue factor (TF)-factor VIIa complex and factor Xa to maintain hemostasis and prevent excessive thrombosis. It is a Kunitz-type serine protease inhibitor, produced mainly by endothelial cells, and circulates bound to lipoproteins or as a free plasma protein. TFPI acts as a feedback inhibitor that ensures balanced thrombin generation, thereby reducing the risk of pathological clot formation. Dysregulation or deficiency in TFPI has been linked to thrombotic disorders and cardiovascular diseases. Beyond its anticoagulant role, TFPI exhibits anti-inflammatory properties, reducing vascular inflammation and protecting against atherosclerosis. It is also involved in angiogenesis and endothelial cell function, making it significant in vascular biology.
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Tissue Factor Pathway Inhibitor (TFPI)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 32.7 kDa Observed MW (SDS-PAGE): 36 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu29-His302 Tag: N-terminal His tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
TFPI
dry ice
No
availability
Shipped within 5-7 working days.
alias
EPI, LACI, TFI, TFPI1,Extrinsic pathway inhibitor,EPI
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
Human TFPI(Tissue factor pathway inhibitor) ELISA Kit

proveedor
FineTestreference
EH0283reactivity
humanstatus
RUOPrecio a consultar
Ver másHorse TFPI(Tissue factor pathway inhibitor) ELISA Kit

proveedor
FineTestreference
EHS0011reactivity
horsestatus
RUOPrecio a consultar
Ver másMouse TFPI(Tissue Factor Pathway Inhibitor) ELISA Kit

proveedor
FineTestreference
EM1398reactivity
mousestatus
RUOPrecio a consultar
Ver más