Rat Thyrotropin-Releasing Hormone Receptor (TRHR) ELISA Kit

Este producto es parte de TRHR - Thyrotropin-Releasing Hormone Receptor
Rat Thyrotropin-Releasing Hormone Receptor (TRHR) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for TRHR

proveedor

Abbexa

reference

abx392060

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Thyrotropin-Releasing Hormone Receptor (TRHR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat TRHR concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

The Thyrotropin-Releasing Hormone Receptor (TRHR) is a G protein-coupled receptor (GPCR) that is activated by thyrotropin-releasing hormone (TRH), a peptide hormone responsible for regulating the secretion of thyroid-stimulating hormone (TSH) from the pituitary gland. TRHR is primarily expressed in the anterior pituitary, where it plays a critical role in the regulation of thyroid function by stimulating the release of TSH. Upon activation, TRHR couples to Gq proteins, stimulating phospholipase C (PLC) and increasing intracellular calcium levels, which in turn promotes the release of TSH and the synthesis of thyroid hormones (T3 and T4). TRHR also plays a role in regulating metabolic processes, growth, and development. Dysregulation of TRHR signaling is implicated in disorders such as hypothyroidism, hyperthyroidism, and thyroid tumors. Targeting TRHR with agonists or antagonists can be useful for managing thyroid-related conditions and regulating thyroid hormone production.

Características del producto

category

ELISA Kits


immunogen target

Thyrotropin-Releasing Hormone Receptor (TRHR)


reactivity

Rat


test range

78 pg/ml - 5000 pg/ml


sensitivity

< 46.9 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

TRHR,TRH receptor,thyroliberin receptor,TRH-R,TRH-R1,CHNG7


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

TRHR


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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