Rat Tachykinin Receptor 2 (TACR2) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
552.5€ (96 tests)
Elisa kits for TACR2
proveedor
Abbexareference
abx256030Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Tachykinin Receptor 2 (TACR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Tachykinin Receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TACR2, also known as NK2R, is another member of the tachykinin receptor family, activated by neurokinin B (NKB) and substance P. Like TACR1, TACR2 primarily couples to Gq proteins, which activate phospholipase C (PLC), generating inositol triphosphate (IP3) and increasing intracellular calcium levels. TACR2 is widely expressed in the smooth muscle, particularly in the respiratory and gastrointestinal systems, where it regulates smooth muscle contraction. In the CNS, TACR2 plays a key role in regulating neurogenic inflammation and modulating pain, as well as contributing to the regulation of reproductive function. Dysregulation of TACR2 signaling has been linked to conditions such as asthma, chronic pain syndromes, and reproductive disorders. Selective TACR2 antagonists are being developed to treat asthma, IBS, and other conditions where neurokinin B-mediated effects contribute to disease pathology.
Características del producto
category
ELISA Kits
immunogen target
Tachykinin Receptor 2 (TACR2)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
sensitivity
0.1 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
TACR2,Neurokinin B receptor,NKNAR,SKR,TAC2R,neurokinin A receptor,NK-2 receptor,P-E receptor,Substance K receptor,NK2R
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TACR2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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