Rat Tachykinin Receptor 2 (TACR2) ELISA Kit

Este producto es parte de TACR - Tachykinin Receptor
Rat Tachykinin Receptor 2 (TACR2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

552.5€ (96 tests)

Elisa kits for TACR2

proveedor

Abbexa

reference

abx256030

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Tachykinin Receptor 2 (TACR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Tachykinin Receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

TACR2, also known as NK2R, is another member of the tachykinin receptor family, activated by neurokinin B (NKB) and substance P. Like TACR1, TACR2 primarily couples to Gq proteins, which activate phospholipase C (PLC), generating inositol triphosphate (IP3) and increasing intracellular calcium levels. TACR2 is widely expressed in the smooth muscle, particularly in the respiratory and gastrointestinal systems, where it regulates smooth muscle contraction. In the CNS, TACR2 plays a key role in regulating neurogenic inflammation and modulating pain, as well as contributing to the regulation of reproductive function. Dysregulation of TACR2 signaling has been linked to conditions such as asthma, chronic pain syndromes, and reproductive disorders. Selective TACR2 antagonists are being developed to treat asthma, IBS, and other conditions where neurokinin B-mediated effects contribute to disease pathology.

Características del producto

category

ELISA Kits


immunogen target

Tachykinin Receptor 2 (TACR2)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


sensitivity

0.1 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

TACR2,Neurokinin B receptor,NKNAR,SKR,TAC2R,neurokinin A receptor,NK-2 receptor,P-E receptor,Substance K receptor,NK2R


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

TACR2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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