Rat T-Cell Surface Glycoprotein CD8 Alpha Chain (CD8A) ELISA Kit
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935106861
info@markelab.com
Precio
578.5€ (96 tests)
Elisa kits for CD8A
proveedor
Abbexareference
abx256377Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat T-Cell Surface Glycoprotein CD8 Alpha Chain (CD8A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat T-Cell Surface Glycoprotein CD8 Alpha Chain (CD8A) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
The CD8A gene encodes the alpha subunit of the CD8 glycoprotein, a key co-receptor expressed on the surface of cytotoxic T lymphocytes (CD8+ T cells). CD8A typically forms a heterodimer with CD8B or a homodimer (CD8αα). This protein plays a central role in T-cell activation and immune surveillance by interacting with MHC class I molecules on antigen-presenting cells. The interaction stabilizes the binding of the T-cell receptor (TCR) to antigenic peptides presented by MHC class I, facilitating signal transduction and T-cell-mediated cytotoxic responses. CD8A expression is essential for the development and maturation of CD8+ T cells in the thymus. It also participates in the immune response against viral infections, tumors, and intracellular pathogens. Mutations or dysregulation of CD8A can impair T-cell function and immune homeostasis.
Características del producto
category
ELISA Kits
immunogen target
T-Cell Surface Glycoprotein CD8 Alpha Chain (CD8A)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.08 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CD8,p32,Leu2,IMD116,CD8alpha,MAL,T-lymphocyte differentiation antigen T8/Leu-2,T-cell surface glycoprotein CD8 alpha chain
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CD8A
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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