Rat T-Cell Differentiation Antigen CD6 (CD6) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein CD6
proveedor
Abbexareference
abx168507Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Cluster Of Differentiation 6 Protein is a recombinant Rat protein expressed in E. coli.
Background
CD6 is a type I transmembrane glycoprotein expressed on the surface of T cells, some B cells, and a subset of natural killer (NK) cells. It plays a critical role in the modulation of immune responses, particularly in T-cell activation, differentiation, and immune synapse formation. CD6 is involved in regulating the threshold of T-cell receptor (TCR) signaling and acts as a co-stimulatory receptor that modulates immune responses. CD6 is expressed in the thymus, where it is involved in T-cell development, including positive and negative selection during thymic maturation. In peripheral tissues, CD6 helps facilitate immune responses against pathogens, while maintaining immune tolerance to self-antigens. Dysregulation of CD6 signaling is implicated in a range of immune-related conditions, including autoimmune diseases, inflammatory disorders, and certain types of cancer.
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
T-Cell Differentiation Antigen CD6 (CD6)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 22.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser477-Pro644 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
CD6
dry ice
No
availability
Shipped within 5-7 working days.
alias
TP120,T-cell differentiation antigen CD6,T12
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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