Rat T-Cell Differentiation Antigen CD6 (CD6) Protein

Este producto es parte de CD6 - CD6 molecule
Rat T-Cell Differentiation Antigen CD6 (CD6) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein CD6

proveedor

Abbexa

reference

abx168507

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Cluster Of Differentiation 6 Protein is a recombinant Rat protein expressed in E. coli.


Background

CD6 is a type I transmembrane glycoprotein expressed on the surface of T cells, some B cells, and a subset of natural killer (NK) cells. It plays a critical role in the modulation of immune responses, particularly in T-cell activation, differentiation, and immune synapse formation. CD6 is involved in regulating the threshold of T-cell receptor (TCR) signaling and acts as a co-stimulatory receptor that modulates immune responses. CD6 is expressed in the thymus, where it is involved in T-cell development, including positive and negative selection during thymic maturation. In peripheral tissues, CD6 helps facilitate immune responses against pathogens, while maintaining immune tolerance to self-antigens. Dysregulation of CD6 signaling is implicated in a range of immune-related conditions, including autoimmune diseases, inflammatory disorders, and certain types of cancer.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

T-Cell Differentiation Antigen CD6 (CD6)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 22.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser477-Pro644 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

CD6


dry ice

No


availability

Shipped within 5-7 working days.


alias

TP120,T-cell differentiation antigen CD6,T12


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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