Rat Substance-P receptor (TACR1) ELISA Kit

Este producto es parte de TACR - Tachykinin Receptor
Rat Substance-P receptor (TACR1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for TACR1

proveedor

Abbexa

reference

abx512806

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Substance-P receptor (TACR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Substance-P receptor concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

TACR1 is a G protein-coupled receptor (GPCR) that is activated by neurokinin A (NKA) and substance P, which are neuropeptides from the tachykinin family. TACR1 primarily couples to Gq proteins, which activate phospholipase C (PLC), leading to the production of inositol triphosphate (IP3) and the release of intracellular calcium. This results in smooth muscle contraction, vasodilation, and increased cell signaling. TACR1 is expressed in various tissues, including the central nervous system (CNS), gastrointestinal tract, and vasculature. In the CNS, TACR1 regulates pain perception, mood, and anxiety, while in the gastrointestinal system, it is involved in regulating motility and inflammation. Dysregulation of TACR1 signaling has been implicated in pain disorders, such as chronic inflammatory pain, and conditions like asthma and irritable bowel syndrome (IBS). Targeting TACR1 with antagonists is being explored as a potential therapy for pain management and other inflammatory diseases.

Características del producto

category

ELISA Kits


immunogen target

Substance-P receptor (TACR1)


reactivity

Rat


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.176 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

TACR1,SPR,Substance P receptor,NK1R,TAC1R,neurokinin receptor 1,NK1 receptor,NKIR


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

TACR1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Human TACR1(Tachykinin Receptor 1) ELISA Kit

Human TACR1(Tachykinin Receptor 1) ELISA Kit

proveedor

FineTest

reference

EH3842

reactivity

human

status

RUO

Precio a consultar

Ver más

Rat TACR1(Tachykinin Receptor 1) ELISA Kit

Rat TACR1(Tachykinin Receptor 1) ELISA Kit

proveedor

FineTest

reference

ER1360

reactivity

rat

status

RUO

Precio a consultar

Ver más

Tachykinin Receptor 1 (TACR1) Antibody

Tachykinin Receptor 1 (TACR1) Antibody

proveedor

Abbexa

reference

abx015349

Tested Applications

ELISA, WB

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Rabbit polyclonal antibody against Tachykinin Receptor 1 protein. Immunogen region is Internal.

52€ (10 µg)

Ver más