Rat Sphingosine 1-phosphate receptor 2 (S1PR2) ELISA Kit

Este producto es parte de S1PR - Sphingosine 1 Phosphate Receptor
Rat Sphingosine 1-phosphate receptor 2 (S1PR2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for S1PR2

proveedor

Abbexa

reference

abx512606

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Sphingosine 1-phosphate receptor 2 (S1PR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Sphingosine 1-phosphate receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

S1PR2 is a G protein-coupled receptor for sphingosine-1-phosphate (S1P), a bioactive lipid that regulates cell migration, proliferation, and vascular integrity. S1PR2 is expressed in endothelial cells, smooth muscle cells, and immune cells, where it couples primarily to G12/13 and Gq proteins. Its activation triggers downstream pathways, including Rho/ROCK and phospholipase C (PLC), leading to actin cytoskeletal reorganization and calcium signaling. S1PR2 plays critical roles in maintaining vascular tone, regulating endothelial barrier integrity, and inhibiting cell migration. It also contributes to immune cell retention in tissues, modulating inflammation and immune responses. Dysregulation of S1PR2 has been linked to inflammatory diseases, cardiovascular dysfunction, and neurodegeneration. In cancer, S1PR2 can act as a tumor suppressor by inhibiting migration and metastasis; however, in some contexts, it promotes inflammation and tumor progression. Targeting S1PR2 is under investigation for therapeutic applications in inflammation, vascular diseases, and cancer.

Características del producto

category

ELISA Kits


immunogen target

Sphingosine 1-phosphate receptor 2 (S1PR2)


reactivity

Rat


test range

0.625 ng/ml - 40 ng/ml


sensitivity

< 0.312 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

S1PR2,AGR16,DFNB68,EDG-5,EDG5,Gpcr13,H218,LPB2,S1P2,endothelial differentiation G protein-coupled receptor 5,G protein-coupled receptor 13,GPCR18 ,S1P receptor 2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

S1PR2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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