Rat Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Protein
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Description
Rat Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat Pigment Epithelium-Derived Factor / PEDF (SERPINF1) (NP_808788.1) (Met1-Thr418) was expressed with a polyhistidine tag at the C-terminus.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Pigment Epithelium-Derived Factor / PEDF (SERPINF1) |
| Host | HEK293 cells |
| Origin | Rat |
| Observed MW | Molecular Weight: 45.9 kDa Sequence Fragment: Met1-Thr418 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q80ZA3 |
| Gene ID | 287526 |
| NCBI Accession | NP_808788.1 |
| Alias | OI6,OI12,PEDF,EPC-1,PIG35,Pigment epithelium-derived factor,Cell proliferation-inducing gene 35 protein,Serpin F1 |
| Background | Protein SERPINF1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
SERPINF1, also known as pigment epithelium-derived factor (PEDF), is a member of the serpin (serine protease inhibitor) family, though it has unique properties distinct from classical serpins. Unlike most serpins, SERPINF1 does not function as a typical protease inhibitor but is instead a multifunctional protein with potent anti-angiogenic, neuroprotective, and anti-inflammatory effects. First identified in the pigment epithelium of the eye, it has since been found in a variety of tissues and is now recognized as a crucial player in many biological processes, including the inhibition of abnormal blood vessel growth and tissue protection. SERPINF1 is highly expressed in the eye, particularly in the retinal pigment epithelium (RPE) and other neural tissues. It is most famous for its role in ocular health, but its functions extend to other organs, such as the liver, heart, skin, and brain.
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